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Details for 1-Deoxynojirimcin

1-Deoxynojirimcin

Category :

Pharmaceuticals and Biochemicals/Herbal Plant Extract

1-Deoxynojirimcin
CAS NO : 19130-96-2
EC NO :
MF : C6H13NO4
MW : 163.1717
Specification : 1-Deoxynojirimcin 12:1
Packing : 25kg/fiber drum I.D.42CM x H52CM
Product description :
Mulberry Leaves Extract 1-DNJ
Latin Name: Morus alba
CAS No.: 19130-96-2
Active Ingredient: 1-Deoxynojirimcin
Specifications: 12:1
Test Method: TLC
Mulberry Leaves Extract Morus alba 1-Deoxynojirimcin
Mulberry leaves have long been used in Chinese medicine for the prevention and treatment of diabetes; they contain compounds that suppress high blood sugar levels.
Mulberry Fights Arterial Plaque
Scientists in Japan have pinpointed a number of biologically active compounds in extracts of the leaves of the white mulberry, Morus alba, a plant that silkworms are crazy about. 1 Not that the silkworms care, but the mulberry-leaf extract turns out to be effective in suppressing the progression of atherosclerosis, the buildup of cholesterol-rich plaque in our arteries. 2 It does this, apparently, by inhibiting the oxidation of LDL-cholesterol (low-density lipoprotein, the ¡°bad cholesterol¡±), which is a major factor in the development of atherosclerotic plaque.
The Japanese researchers reached this conclusion based on their observations of the antioxidant effects of the mulberry extract on LDL-cholesterol taken from both rabbits and humans. They believe that the agents primarily (but not exclusively) responsible for this effect are two closely related compounds, isoquercitrin and astragalin. The former contains, as part of its molecular structure, the well-known antioxidant flavonoid quercetin, which is found in many foods and in a variety of nutritional supplements.
In studying the antioxidant effects of the whole mulberry-leaf extract and, separately, of the compound isoquercitrin, as well as of the compound quercetin (which is not found as such in mulberry), the researchers observed that all were effective but that isoquercitrin was somewhat less effective than the same amount of quercetin. They also reported, however, that when isoquercitrin is ingested (by mice), it is largely metabolized to quercetin. Thus, although quercetin is not found in mulberry, mulberry is still a good source for it (and the silkworms still couldn¡¯t care less).
Profile
Botanical resouce: mulberry leaf, Morus alba L.
Latin Name: Folium Mori, Ramulus Mori
Part of Plant Used: Leaf
Active Ingredient: 1-Deoxynojirimycin (1-DNJ)
Specifications: 1%~20%
Testing Method: HPLC
CAS: 19130-96-2
Molecular Formula: C6H13NO4
Molecular Weight: 163.17
Appearance: Brown Powder
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Description
Morus alba, known as white mulberry, is a short-lived, fast-growing, small to medium sized mulberry tree, the species is native to northern China, and is widely cultivated and naturalized elsewhere. Extract derived from the leaves of the mulberry tree may yield health benefits when used medicinally.
About 1-deoxynojirimycin
Mulberry leaf has a substance called moranoline (1-deoxynojirimycin) that inhibits an enzyme in the intestinal tract (alpha-glucosidase) involved in the digestion of carbohydrates. Moranoline holds back complex carbohydrates, starches, maltose and sucrose from breaking down into glucose.
Properties
antihyperglycemic, antioxidant and anti-glycation
Benefits
Blood Sugar Balance,prevent diabetes mellitus 
Liver and Lung Remedy
Weight loss
Application

Medicine ,cosmeitcs ,dietary supplement ,food aditive , food for livestock,tea

Uses : pharmaceutical, health food,cosmetic
Synonyms : Deoxynojirimycin;(2r,3r,4r,5s)-2-hydroxymethyl-3,4,5-trihydroxypiperidine;1,5-dideoxy-1,5-imino-d-glucito;1,5-dideoxy-1,5-imino-d-glucitol;1-deoxynojirimicin;1-deoxy-nojirimyci;5-amino-1,5-dideoxy-d-glycopyranose;5-dideoxy-5-amino-d-glucopyranos;5-piperidinetriol(2r-(2alpha,3beta,4alpha,5beta))-2-(hydroxymethyl)-4;(2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol;
Molecular Structure : 1-Deoxynojirimcin 19130-96-2
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