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Argatroban Intermediate 74874-08-1
Category : Pharmaceuticals and Biochemicals
CAS NO : 74874-08-1 EC NO : MF : C15H29ClN6O5 MW : 408.88096 Product description : Argatroban is given intravenously and drug plasma concentrations reach steady state in 1-3 hours.Argatroban is metabolized in the liver and has a half-life of about 50 minutes. It is monitored by PTT. Because of its hepatic metabolism, it may be used in patients with renal dysfunction. (This is in contrast to lepirudin, a direct thrombin inhibitor that is primarily renally cleared). Chemical data Formula C23H36N6O5S Mol. mass 508.635 g/mol Synonyms : Ethyl (2R,4R)-1-(Nitroglycerine-nitro-L-arginyl)-4-methyl-piperidinecarboxylate hydrochloride;(2R,4R)-ethyl 1-((s)-2-amino-5-(3-nitroguanidino)pentanoyl-4-methylpiperidine-2-carboxylate; Molecular Structure : 
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Argatroban Intermediate